A member asked:

Can i drink alcohol with levaquin (levofloxacin) and prednisone? will it diminish the effects?

4 doctors weighed in across 2 answers

You shouldn't: It would help to know why you are on Levaquin (levofloxacin) and predisone, but i will guess it is a pulmonary infection. Alcohol in amounts more than social drinking (1-2 drinks/day) impairs the cough reflex, increases chances of aspiration, damages our immune system and increases side effects of prednisone, especially stomach irritation/bleeding. If alcohol has become a problem for you, seek help.

Answered 7/1/2018

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Dr. Connie Topliff answered

Specializes in Family Medicine, Board Certified

See below: Both Levaquin (levofloxacin) and Prednisone can irritate the stomach, and alcohol can intensify this effect. While alcohol shouldn't decrease their effectiveness, the 3 together might make you nauseated or have stomach irritation. I'd recommend not indulging until you've finished both of your prescriptions.

Answered 7/1/2018

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