A member asked:

Can suboxone cause low t in males? if so how common is this? i'm 33 have taken sub for 4 years and really struggle from fatigue.

5 doctors weighed in across 2 answers
Dr. Alvin Lin answered

Maybe . . .: Suboxone is a brand name for combination of Buprenorphine & naloxone. Buprenorphine is an opioid agonist-antagonist while Naloxone is strictly an antagonist. It's used in opioid dependence. Chronic opioid use can affect pituitary function and thus lower testosterone production leading to hypogonadism symptoms such as fatigue & loss of libido. Check your t level and get treated if appropriate.

Answered 6/30/2014

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Dr. Brian Le answered

Specializes in Pain Management

Yes: Suboxone is an opioid. Chronic use of any opioid might lead to hypogonadism with decreased hormonal level. Your fatigue might be a result of low testosterone, but also can be results of other medical conditions. Please see your doctor for evaluation.

Answered 9/13/2013

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