Can i take benadryl (diphenhydramine) after taken a claritin?

Mixed antihistamines: You can but the benedryl can make you very sleepy. Men with prostate issues could experience difficult urination. See an allergist or ENT doc for definitive solutions.

Not recommended: Claritin is a slow release, non-sedating antihistamine. Benadryl (diphenhydramine) is a faster onset sedating antihistamine. Taking both will have additive effects and possible adverse effects such as sedation. It is not recommended that you take both of these without the guidance of your doctor. If the Claritin is not adequate for your symptoms, there are many other medications that can be prescribed to help.