U.S. doctors online nowAsk doctors free
Montgomery, AL
A 83-year-old female asked:

Why can't you take lomotil and imodium (loperamide) together?

2 doctor answers3 doctors weighed in
Dr. Patrick Sweet III
Pathology 22 years experience
Synergy: Both Lomotil & Imodium (loperamide) contain a mu opioid receptor agonist that acts in the meyenteric plexis in the GI tract. You run the risk of potential synergism whereby the effects of one increases the others potency leading to supra therapeutic effects or even a complication ileus (paralysed bowel). That said, you should follow the guidance of the physician that is managing your GI disease in this matter.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Evans Prieston
Pharmacology 46 years experience
Lomotil + Imodium (loperamide): Imodium (loperamide) have similar mechanisms of action. I have seen dosages of Imodium (loperamide) and Lomotil alternated as often as every 3 hours. Do not exceed 8 tablets of either drug within a 24 hour period without first consulting your physician.
Created for people with ongoing healthcare needs but benefits everyone.

Similar questions

A 43-year-old member asked:

Can you take imodium (loperamide) and lomotil together?

1 doctor answer1 doctor weighed in
Dr. Vivek Huilgol
Gastroenterology 37 years experience
No: This is not a good idea.
Created for people with ongoing healthcare needs but benefits everyone.
A 49-year-old member asked:

What is the difference between lomotil and imodium (loperamide)?

1 doctor answer2 doctors weighed in
Dr. Neelesh Tipnis
Pediatrics - Gastroenterology 26 years experience
Both work the same: Both Lomotil and Imodium (loperamide) contain opiod (narcotic) agonists which act to decrease muscle contraction in the small intestine and colon.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Sep 16, 2018
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.