A member asked:

Why can't you take lomotil and imodium (loperamide) together?

3 doctors weighed in across 2 answers
Dr. Patrick Sweet III answered

Specializes in Pathology

Synergy: Both Lomotil & Imodium (loperamide) contain a mu opioid receptor agonist that acts in the meyenteric plexis in the GI tract. You run the risk of potential synergism whereby the effects of one increases the others potency leading to supra therapeutic effects or even a complication ileus (paralysed bowel). That said, you should follow the guidance of the physician that is managing your GI disease in this matter.

Answered 5/2/2018

5.4k views

Thank
Dr. Evans Prieston answered

Specializes in Pharmacology

Lomotil + Imodium (loperamide): Imodium (loperamide) have similar mechanisms of action. I have seen dosages of Imodium (loperamide) and Lomotil alternated as often as every 3 hours. Do not exceed 8 tablets of either drug within a 24 hour period without first consulting your physician.

Answered 9/16/2018

5.4k views

Thank

Related Questions

A member asked:

I take 21 imodium (loperamide) a day , is this safe?

A doctor has provided 1 answer

A member asked:

Is imodium (loperamide) safe to take if I have gastritis?

A doctor has provided 1 answer

Online Primary Care Doctors Accepting New Patients

$44 video appointments available today with a membership as low as $15/month

Book a Video Appointment
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question