Neulasta (pegfilgrastim): For ac regimen dose dense (every 2 weeks, we recommend neulasta). After that i usually give Taxol (also called paclitaxel) weekly x 12 weeks and Neulasta (pegfilgrastim) is not used for weekly regimen. Some oncologists prefer Taxol every 3 weeks x 4 doses (big dose taxol), than it can be used. Weekly regimen have robust data and is well tolerated and we can avoid side effects of Neulasta (pegfilgrastim) (which can be rough).
Answered 4/17/2016
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Variable : There are two commonly used Taxol regimens int this situation. One is every 3 weeks for 4 cycles the other is weekly for 12 cycles. A significant number of my every 3 week patients require/benefit from neulasta (pegfilgrastim).
Answered 5/29/2018
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