A member asked:

What is flexeril versus skelaxin (metaxalone)?

5 doctors weighed in across 2 answers
Dr. David Rosenfeld answered

Specializes in Pain Management

See below: Both are muscle relaxers. Both have the same adverse effects. My experience is that skelaxin (metaxalone) is less sedating than flexeril.

Answered 4/14/2020

5.4k views

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Dr. Paul Grin answered

Specializes in Pain Management

Flexeril & skelaxin (metaxalone): Skelaxin) is thought to act by suppressing postsynaptic spinal cord and trigeminal reflexes. Flexeril (cyclobenzaprine hcl) is TCA with centrally acting muscle relaxants properties.

Answered 11/25/2019

3.5k views

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