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A 27-year-old female asked:

My one year old has high monocytes (1.8 absolute) and low neutrophils (0.5 absolute) could this be an indication of leukemia?

3 doctor answers4 doctors weighed in
Dr. James Ball
Pediatric Hematology and Oncology 20 years experience
Viral more likely: The low neutrophils should be followed. The most common cause for the low neutrophils is some type of infection (usually viral infection). If this is so, i would expect things to get better within a month's time. Leukemia often causes other blood counts to be low (platelets, hemoglobin). But do have the blood counts followed in a few weeks.
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Dr. Scott Diede
A Verified Doctoranswered
30 years experience
Unlikely...: As mentioned, viruses can transiently cause low neutrophils. Another cause could be auto-antibodies directed toward neutrophils (also temporary). An increased monocyte count is usually the body's natural response to low neutrophils to help fight infection. If other counts (red blood cells or platelets) go low or new concerning symptoms (unexplained fevers), may need further evaluation (peds heme).
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Agos Luca
Specializes in Pathology
Probably not: At this age, the most likely cause for neutropenia (low neutrophils) accompanied by mild absolute monocytosis (normal is about 1) is an infection, most commonly viral. Consulting with your pediatrician is recommended.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 20, 2020

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