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A member asked:
2 positive ana titres 1:160 speckled. all manual diff tests neg. is this something to worry about?
2 doctors weighed in across 2 answers
Possibly: The ANA is not very specific. It can be possible in numerous diseases including viral diseases. It can also be positive in individuals without any disease. The ANA needs to be interpreted in the clinical setting to be properly evaluated.
Answered 6/10/2014
5.4k views
May be non-specific?: ANA is test for antibodies directed against nuclear antigens. A positive test screens for autoimmune diseases such as systemic lupus erythematosus. There are four patterns: homogenous, nucleolar, peripheral, and speckled. Low titers less than 1:160 is likely a non-specific response. The clinical importance of this is to be decided in the light of other findings, and a follow-up test for direction.
Answered 10/22/2015
5.4k views
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A member asked:
I have been lethargic and generally unwell with constant headaches for two months. Blood test show raised crp, ESR and positive for ana. What's wrong?
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