Do antihistamines cause gout?

No: There is a letter to the editor in a european journal reporting an association. That was in 1950. Since then nothing. To the best of my knowledge antihistamines are not associated with gout.

No: There is no proven association of antihistamine medications and gout.

Typically no: Antihistamines are generally not considered a group of medications that directly cause gout. However, antihistamines can cause dryness, and if that progresses to dehydration, then gout attacks can occur with a higher frequency. This would be an indirect cause. Antihistamines generally don't cause significant dehydration. Aspirin can make gout worse, as can other salicylate-containing meds.

No: Antihistamines do not cause gout.