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A member asked:
How come the sebum production can be reduced by accutane without treating its cause , the hormones? can you please explain the mechanism?
4 doctors weighed in across 3 answers
Not understood: The multiple effects of Isotretinoin are not completely understood. Particularly how it stops oil production or thickening of keratin. It also has an antiinflammatory effect. Only very specific forms of acne respond to isotretinoin. It is in the retinoid family which includes vit a & can very dangerous to fetus developing brain. Can cause severe depression. How this happens is not understood.
Answered 6/26/2014
5.4k views
Cells: Accutane reduces the proliferation of cells that make sebum, while the hormones stimulate the cells that are there to make more (or less) sebum.
Answered 6/24/2014
5.4k views
Accutane: Accutane is 13 cis retinoic acid. . When we eat vitamin a it is fat soluble and is stored int he liver. When the body needs vitamin a the storage form is converted in to 13 cis retinoic acid, which is water soluble and is eliminated from the body quickly. One of it's actions is to affect the formation of the sebaceous glands, minimizing their size and oil production.
Answered 11/29/2017
5.4k views
Related Questions
A member asked:
What is a good diet for someone who's taking Isotretinoin/Accutane, but is trying to lose weight at the same time due to Obesity that causes the hormonal imbalance?
2 doctors weighed in across 2 answers
A member asked:
After taking Accutane what will be the other symptom of excess androgens in females if Accutane stops the sebum without reducing DHT levels?
A doctor has provided 1 answer
A member asked:
Can 2 full courses of Accutane induce permanent sebum over-activity reduction?Will sebum hyperactivity resume bk to pre-accutane state after stopping?
A doctor has provided 1 answer
A member asked:
Is there anyone that has any idea of how to return your body to equilibrium after taking accutane? Referring to cell proliferation and sebum output.
A doctor has provided 1 answer
A member asked:
I took Accutane 40mg. I've been off 3 months. I am scheduled for fractional co2 laser next week. My face is producing sebum but should I wait 6 mos?
A doctor has provided 1 answer
People also searched for:
Y doctors prescribe Accutane when its mechanism is not completely understood that how it reduces the sebum without affecting hormones?
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