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A 33-year-old member asked:

What gene do i need to get tested for the familial colon cancer?

3 doctor answers9 doctors weighed in
Dr. Edward Gold
Internal Medicine 44 years experience
HNPCc: Hereditary nonpolyposis colorectal cancer.
Dr. Allen Kamrava
Colon and Rectal Surgery 15 years experience
Not so simple: There are a few genes we test for now for familial colon cancer: fap, msh-1/mlh-2, myh ... But you can't simply get tested out of the blue. A family member with the colon cancer has to be first tested. If any of those genes are found, then the relatives are tested for those specific genes.
Dr. Richard Roberts
Pediatrics 46 years experience
Need more info: Totally different genes predispose to colon cancer, including BRCA 1 and 2; Familial Adenomatous Polyposis develops so many polyps in the colon they may be too numerous to count--but this one is quite rare. The commonest is Hereditary Non-Polyposis Colon Cancer. You may be at increased risk if close family members have developed it. See http://www.hopkinscoloncancercenter.org/CMS/CMS_Page.aspx?

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Last updated Nov 23, 2015
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