A member asked:

Can 900 mg of gabapentin at bedtime for 6 weeks cause ast and alt enzymes to be elevated 3-4 points above top of 'normal'. never had issue before.?

5 doctors weighed in across 4 answers

Possible: Many medications can exhibit mild adverse effects on the liver, and not unusual to see slight elevations of liver enzymes. No need to stop med unless the elevation is more than 3 times normal, in most cases. Talk to your doc about whether you should continue gabapentin.

Answered 2/23/2013

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Maybe: That dose of Gabapentin should not cause liver inflammation or impairment in a normally functioning liver. That said, 3-4 points above normal for lab value could easily be lab error or insignificant. Many drugs are metabolized by the liver so in evaluating changes in liver enzymes you need to look at everything you're taking - even tylenol (acetaminophen). It could be a combination of meds.

Answered 6/25/2014

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Dr. Alan Ali answered

Specializes in Psychiatry

Liver enzymes: Mild elevation in liver enzymes calls for repeat liver function tests. Consult your primary care doc.

Answered 2/23/2013

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Dr. Alan Ali answered

Specializes in Psychiatry

SOB/Anxiety: Sure, but need to rule out all other physical causes of sob, thru thorough exam by your primary care doc.

Answered 2/23/2013

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