A member asked:

What is myelodysplastic syndromes (mds)?

8 doctors weighed in across 4 answers

Definition: The myelodysplastic syndromes (mds) comprise a heterogeneous group of malignant stem cell disorders characterized by dysplastic and ineffective blood cell production and a variable risk of transformation to acute leukemia.

Answered 10/3/2020

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Bone narrow disease: This is a group of disease that result in bone marrow failure. This can present as anemia or low blood counts. There are several forms of the disorder. Some have long histories and courses and some quickly turn to leukemia. A bone marrow and special test on it are needed to determine the type, treatment, and benefit of treatment.

Answered 10/3/2020

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Dr. Agos Luca answered

See below...: Myelodysplastic syndrome (mds) is a form of bone marrow cancer that is generally less aggressive than leukemia but nevertheless still malignant. Mds usually evolves more slowly then leukemia and sometimes can transform into acute leukemia and become more aggressive and faster evolving.

Answered 2/16/2020

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Dr. Matthew Fero answered

Specializes in Medical Oncology

Bone marrow disease: MDS is a disease of bone marrow that causes blood precursor cells to have an abnormal appearance ("dysplasia"), and prevents normal production of mature RBC or WBC. This can cause seriously low blood cell counts. It arises from gene mutations acquired during your lifetime, in bone marrow cells. There is a risk that, with additional mutations, it can evolve into acute leukemia.

Answered 10/3/2020

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