A 45-year-old member asked:
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can narcan (naloxone) cause a false positive on a drug screen test?

3 doctor answers
Dr. Jon Ahrendsen
38 years experience Family Medicine
NO: According to an journal article by storrow in the archives of emergency medicine vol 24 issue 6 in 1995. When 14 volunteers had urine drugs screens done after IV naloxone, all urine samples were negative. But the only reason to get Naloxone is if you took too much narcotic. That orginial narcotic in your system likely would make the urine drug screen positive.
Answered on Jun 30, 2014
Dr. Ravi Srivastava
35 years experience Addiction Medicine
No: No.
Answered on Jul 5, 2012
Dr. Heidi Fowler
24 years experience Psychiatry
No, it does not.: “Does naloxone cause a positive urine opiate screen?” “Although the metabolites of naloxone hydrochloride are similar in structure to oxymorphone and are excreted in human urine for several days, naloxone was not associated with a positive enzymatic urine screen for opiates.” REF: https://www.ncbi.nlm.nih.gov/pubmed/7978599
Answered on Nov 16, 2018

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A 36-year-old member asked:
Dr. Benjamin Nguyen
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No: Narcan (naloxone) cannot produce a false negative drug screen. Narcan (naloxone) merely competitively inhibits opioids at the opioid receptor.
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7 thanks
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Dr. Romanth Waghmarae
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