A member asked:

Can you pass on a sickle cell disease to your child?

3 doctors weighed in across 2 answers

Depends on partner: Sickle cell disease requires that the s gene be passed to a baby during conception from both parents. In theory, someone with sickle cell disease could only pass one gene, so if the partner had normal hemaglobin genes, the baby would have trait, not ss. If the partner had trait, both trait or ss is possible. If both parents have sickle cell ss disease, all their babies would have sickle cell.

Answered 7/20/2012

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Yes: Sickle cell disease is a hereditary disease. If the mother and father pass on only one copy of the affected gene then it is sickle cell trait. However, if two abnormal copies of the gene are passed on--one from mother and one from father than the child will have sickle cell disease.

Answered 3/18/2016

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