A member asked:

What are the effects of overdose on migraten (apap/caffeine/isometheptene mucate)?

5 doctors weighed in across 2 answers

Serious: Acetaminophen (apap) is one of the most commonly overdosed over-the-counter medications; overdose can seriously damage the liver & can kill. Isometheptene overdose can raise the blood pressure & heart rate to dangerous levels. Blood pressure high enough can cause blindness, heart attack, stroke. It is very important not to take more than instructed of any prescribed or over-the-counter medication.

Answered 6/25/2020

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Liver dysfunction: Any drug that contains apap (Tylenol) should be taken as directed as large amounts can result in liver damage. Excessive amounts of caffeine and isometheptene can cause an increase in blood pressure, heart rate and heart arrhythmias. All prescribed and over the counter drugs should be taken as instructed with careful attention not to exceed recommended amounts.

Answered 7/15/2018

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