A member asked:

Is there any degenerative brain diseases caused by liver disease?

6 doctors weighed in across 2 answers

Hepatic encephalopat: Hepatic encephalopathy is probably not truly a degenerative brain disease, but it certainly causes confusion. It is caused by a build-up of ammonia from liver failure (eg cirrhosis). Some ailments such as alcoholism and wilson's disease that can cause liver failure are associated with degenerative brain diseases, the cerebral degeneration in those ailments is not directly from liver disease.

Answered 6/25/2020

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Dr. Michael Depietro answered

Specializes in Pulmonary Critical Care

Yes: Chronic poorly controlled liver disease can lead to a condition of brain injury called hepatocerebral degneration. This is not to be confused with the delirum that is seen with liver failure and is reversible ( hepatic encephalopathy). Hepatocerebral degeneration is a less reversible problem seen after years of advanced liver disease and has features like Parkinson's disease, .

Answered 2/18/2015

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