What are the causes of coronary artery blockage?

Several: There are a number of risk factors that lead to plaque in the coronary arteries which is the reason for the blockage. Some of these are smoking, high blood pressure, unhealthy diet, an abnormally high cholesterol, lack of exercise, and obesity. There are also hereditary factors.

Multifactorial : A plague formation that occlude the artery. Compose of cholesterol, fibrin products, calcium, inflammatory cells and mediators etc. Started by an injury at the intima, the inner part of the artery. Then the plague formation. Risk are increase age, smoking, high cholesterol and ldl, htn, diabetes.