A member asked:

Is it unusual for the radiation therapy for lung cancer to make someone lose his voice?

10 doctors weighed in across 2 answers

Yes: The vocal cords when treated directly could cause this so in lung cancer thats not likely. However the left vocal cord has a nerve that goes down in the chest then comes back up to the cord. There may be cancer in the mediastinum that is compressing this nerve leading to the hoarseness. Radiation by itself in the usual fractioned (6 week) course shouldn't. With cyberknife it may happen.

Answered 3/12/2020

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Dr. Reza Shirazi answered

Specializes in Radiation Oncology

Yes: Loosing voice can be due to direct invasion of the larynx (far from lung) or laryngeal nerve compression or damage ( recurrent laryngeal nerve in the chest). Advanced cancer can be pressing on this nerve and cause voice loss. If there is no voice loss to start with, it is unusual for radiation to damage the nerve in typical dose fractionation.

Answered 6/30/2013

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