Should prograf or cellcept (mycophenolate mofetil) increase the blood sugar level?

Both can increase: Blood sugar may go up in response to either of these medications.

Diabetogenic prograf: Tacrolimus (Prograf) is known to be diabetogenic and as much as 20-25% of renal transplant recipients who did not have diabetes prior to transplant surgery develop post-transplant diabetes. Mycophenolate mofetil (Cellcept) is not known to cause hyperglycemia.