Was on wellbutril xl for yrs and switched to viibryd (vilazodone hydrochloride). felt great depression/anxiety wise but noticed rapid weight gain; same with lexapro. options?

Your choice: Wellbutrin does not have weight gain associated but works differently than viibryd (vilazodone hydrochloride). If the viibryd (vilazodone hydrochloride) is working well for you, then try to fight the weight gain with regular exercise and reduction of your portion sizes.

Different mechanisms: Viibrid is the newest member of a class of drugs affecting mainly the serotonin neurotransmitters in the brain. It is less likely to cause weight gain than other medicines in its class (i.e. Lexapro). Since it was effective on the depressive symptoms perhaps your md could add back the wellbutrin (bupropion). Also healthy eating and exercise should also be included in your treatment.