A member asked:

Metformin, zocor, (simvastatin) lisinopril could any of these affect nervous system?

6 doctors weighed in across 2 answers

Not common : What do you mean aby nervous side effects? Anything in medicine can cause something or some type of side effect. The golden question is : is it common to cause nervous side effectrs and the answer is absolutely not. What i intermittently encountered that metformin can cause shortness of breath which can cause much anxiety.

Answered 11/23/2014

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Dr. K. Olson answered

Specializes in Psychiatry

Yes: Metformin used chronically can deplete B12 - this can cause peripheral neuropathy (lack of sensation and tingling in arms and legs), memory problems, and depression. Zocor (simvastatin) can prompt aching in muscles - a not uncommon side effect.

Answered 10/23/2017

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