A member asked:

What are the causes of dupuytren's contracture?

7 doctors weighed in across 6 answers
Dr. Eon Shin answered

Specializes in Hand Surgery

Mainly genetic.: Dupuytren's contracture is usually seen in persons of northen european ancestry. There are associated diseases that can be seen in dupuytren's contracture, such as epilepsy, diabetes mellitus, and alcoholism. Dupuytren's contracture is not work-related or activity-related.

Answered 11/7/2015

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Dr. Raymond Raven answered

Specializes in Hand Surgery

Not known: Some researchers believe that dupuytren's disease may be due to an autoimmune reaction, in which a person's immune system attacks its own body. A number of factors are believed to increase the risk of dupuytren's disease, including age, sex, ancestry, tobacco use, and disease such as diabetes and epilepsy (most likely associated with seizure medication).

Answered 9/17/2015

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Spontaneous: Whike there is an association with trauma, alcohol use, certain drugs and while there is some genetic basis, for all practical purposes it happens spontaneously. That is, there is really no good prevention. Focus is typically on treatment if contractures get bad enough.

Answered 12/4/2012

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Mostly genetic: Dupuytren's contracture is a fibroproliferative disorder with a strong family history. Almost 2/3's of people with this disease have an affected family member. There are some associations with diabetes, alcoholism, and the occasional post-injury case. For the most part it is transmitted within families with some northern european ancestry. Disease causes nodules, cords and finger contractures.

Answered 2/4/2017

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Dr. Jeffrey Wint answered

Specializes in Hand Surgery

Fibromatosis: Dupuytren's is an abnormal fibro-proliferative disorder also called palmar fibromatosis know as vikings disease it has a significant familial and genetic etiology here is a link to some additional ideas on facebook regarding dupuytren's https://www.Facebook.Com/pages/dupuytrens-disease-new-treatment-updates/147337105335050?Ref=hl.

Answered 12/10/2013

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Dr. Gary Pess answered

Specializes in Hand Surgery

Hereditary: Most people believe the primary cause is genetic / hereditary. Trauma can stimulate the disease in someone with a predisposition. It is also associated with epilepsy, alcoholism and diabetes.

Answered 11/30/2013

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