Can osteogenesis imperfecta affect more than just bone structure?

YES...: This is a condition that affects all bones in the body - with a great degree of variability amongst patients in the severity of the disease. There are several types known, and symptoms are quite different depending on the type. What is common is the brittle bone - in mild forms the fractures occur in childhood and stop after adulthood. Some patients have hearing loss/tooth problems.

YES: Blue sclera, poor muscle tone, early loss of hearing in some children, slight protrusion of the eyes.