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A 43-year-old female asked:

Do antacids deplete b12?

2 doctor answers2 doctors weighed in
Dr. Dan Fisher
Internal Medicine 28 years experience
Theoretically: Lack of stomach acid can cause impaired release of B12 from food. Typical antacids (tums, mylanta, etc) and intermittent use of other agents are not likely sufficient to affect this in any clinical way, but proton pump inhibitors such as Omeprazole when taken daily for long periods of time can cause vit B12 deficiency.
Dr. Diane Culik
46 years experience
Often: Antacids may interfere with B12 absorption. The worst are the strong acid blockers like Prilosec and nexium (esomeprazole).. See the book "could it be b12".

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Last updated Oct 3, 2016

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