What causes a deep vein thrombosis?

Many factors: Patients with a hereditary condition, called venous insufficiency have a valvular condition that allows blood to pool while standing or sitting, decreased return to heart when not lying down. Can lead to inflammation due to decreased blood flow through the vein, damage to vein and blood clotting. Other factors blood clotting disorder, malignancy, recent surgery, hx dvt, pregnancy, hrt, infection.

Virchow's Triad: The causes of DVT center on 3 important factors which can act alone or together known as virchow's triad. The 3 factors are: 1. Stasis (sluggish flow in the veins) — limited mobility or venous insufficiency. 2. Injury to the vein — trauma, IV inserts, surgery, circulating toxins and bacteria. 3. Hypercoagulable states- from a genetic predisposition or non-genetic such as smoking, cancers, etc.

Multiple.: There are many causes for DVT but all causes revolve around 3 factors: stasis of blood, injury to the vessel wall or increased propensity to clot(hypercoagulabe state). Stasis occurs with long trips or immobility due to illness or casts. Injuries to the vein wall can occur with trauma from something within the vein or external to it .Hypercoagulable- increased risk of clotting -genetic/acquired.