A member asked:

I take actonel (risedronate). how can this give me an infection after dental extraction?

8 doctors weighed in across 4 answers
Dr. Peter Karsant answered

Specializes in Dentistry

Literature: Did not see this in the literature. Common side effects are back pain and bladder infection. Ask your dentist or pharmacist for more information.

Answered 3/22/2020

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Depends: Some recent studies have shown an increased risk of "osteomyelitis" (bone infection) not 100% sure why, theory is, bone density increases, "squeezing" the blood vessels thereby reducing healing potential. Talk to your dentist about other options i.e. Root canal therapy or your md about a drug holiday.

Answered 6/7/2015

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Bisphosphonates: Actonel (risedronate) is one of several medications that is part of a class of drugs called bisphosphonates. They are used to treat osteoporosis and similar diseases. Serious problems with bone healing (osteonecrosis), particularly after dental surgery, have been found in some people taking bisphosphonates. It is more likely to occur if you are receiving the medication intravenously. Make sure to tell your dds.

Answered 6/24/2014

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Osteoclasts: Bisphosphonates irreversibly inhibit the bone cell that remodels bone (osteoclast), which is necessary for bone healing. Oral side effects are dose dependent and oral bp's are less potent than IV bp's. Complications begin to increase after 3-5 years of oral BP use. Make your dentist/oral surgeon aware of this medication. They will advise you as to how to proceed safely with any recommended care.

Answered 9/28/2016

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