A member asked:

What major illnesses can cause chronic hives?

3 doctors weighed in across 2 answers

Collagen vascular: While most cases of chronic urticaria are idiopathic and are not related to major illnesses, there are cases that are caused by collagen vascular diseases such as lupus. Hepatitis can also cause hives. I have seen it with mycoplasma infections and very rarely it can be associated with certain malignancies.

Answered 3/21/2016

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Dr. Kristin Sokol answered

Specializes in Allergy and Immunology

Chronic urticaria: Chronic urticaria and angioedema is a common condition. Most patients have no underlying disorder. Some illnesses that have been linked to chronic urticaria include: chronic infections (HIV, Hepatitis, parasitic infections, H.pylori), autoimmune disease (lupus), thyroid disorders, and malignancy.

Answered 4/6/2016

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