A member asked:

What is seronegative rheumatoid arthritis?

6 doctors weighed in across 2 answers

Blood test negative : For ra. Seronegative rheumatoid arthritis is the rheumatoid arthritis in which the blood doesn’t contain rheumatoid factor (rf or rhf). While diagnosing ra, doctors get a range of laboratory tests done and also evaluate the physical symptoms.

Answered 3/11/2023

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A bad term: This is a misleading term. It used to be used for individuals who had a different form of arthritis from rheumatoid. However, simple absence of rheumatoid factor (the determinate of seronegativity) does not rule out the diagnosis, nor does the presence of rheumatoid factor confirm the diagnosis.

Answered 2/18/2020

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