A 40-year-old member asked:
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what is seronegative rheumatoid arthritis?

2 doctor answers
Dr. Ahmad M Hadied
48 years experience Orthopedic Surgery
Blood test negative : For ra. Seronegative rheumatoid arthritis is the rheumatoid arthritis in which the blood doesn’t contain rheumatoid factor (rf or rhf). While diagnosing ra, doctors get a range of laboratory tests done and also evaluate the physical symptoms.
Answered on Mar 18, 2020
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Dr. Bruce Rothschild
47 years experience Rheumatology
A bad term: This is a misleading term. It used to be used for individuals who had a different form of arthritis from rheumatoid. However, simple absence of rheumatoid factor (the determinate of seronegativity) does not rule out the diagnosis, nor does the presence of rheumatoid factor confirm the diagnosis.
Answered on Feb 18, 2020
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