U.S. doctors online nowAsk doctors free
CA
A 44-year-old member asked:

Is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma, and pregnancy? why?

2 doctor answers2 doctors weighed in
Dr. Bud Kurwa
Specializes in Ophthalmology
Yes: In patients with closable angles any dilating agent is dangerous as it can precipitate an attach of acute angle closure glaucoma. Anti histamines are contraindicated. Best to see an ophthalmologist and get the angles checked. If they are indeed narrow and closable a laser procedure should be done to prevent a future attack.
Dr. Barbara Stark Baxter
Allergy and Immunology 42 years experience
Anti-cholinergic : Diphenhydramine's anticholinergic effects are to blame. They cause it to aggravate increased intraocular pressure, and dry secretions in those having asthma attacks, making it hard to clear secretions. Here's a link: http://answers.Yahoo.Com/question/index?Qid=20090328145710aa3jfbq the link is wrong about pregnancy, though. It's category b, not c, for pregnancy and considered safer than other meds.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership

Similar questions

A 41-year-old member asked:

Is it true that diphenhydramine is contraindicated in narrow angle glaucoma, acute asthma and pregnancy?

3 doctor answers10 doctors weighed in
Dr. Victor Bello
Ophthalmology 52 years experience
DPH & Asthma, glauco: Diphenhydramine(dph), benadryl, (diphenhydramine) is an antihistaminic having an Atropine like effect, i.e. In asthma is dries up secretions in the bronchi ( the respiratory pipes), thus it worsens asthma. In glaucoma it can precipitate an acute angle closure glaucoma, yes it is unwise to use it. On other side effect is lethargy and in pregnancy it is also unwise to unnecessarily sedate the fetus. So, yes yes yes.
A 37-year-old member asked:

Please explain why is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma and pregnancy?

1 doctor answer5 doctors weighed in
Dr. Richard Williams
Pharmacy 18 years experience
Side effects: Antihistamines like Diphenhydramine have side effects that effect a certain part of the nervous system (cholinergic) which would cause bronchoconstriction, and further closing of the "angle" in glaucoma (angle closure type). If you must take an antihistamine, speak to your physician about antihistamines that do not or minimally affect this system. Good luck.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Feb 17, 2021

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.