A 44-year-old member asked:
Is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma, and pregnancy? why?
2 doctor answers • 2 doctors weighed in
Specializes in Ophthalmology
Yes: In patients with closable angles any dilating agent is dangerous as it can precipitate an attach of acute angle closure glaucoma. Anti histamines are contraindicated. Best to see an ophthalmologist and get the angles checked. If they are indeed narrow and closable a laser procedure should be done to prevent a future attack.
6.3k viewsAnswered >2 years ago
Allergy and Immunology 42 years experience
5.8k viewsAnswered >2 years ago
A 41-year-old member asked:
Is it true that diphenhydramine is contraindicated in narrow angle glaucoma, acute asthma and pregnancy?
3 doctor answers • 10 doctors weighed in
Ophthalmology 52 years experience
DPH & Asthma, glauco: Diphenhydramine(dph), benadryl, (diphenhydramine) is an antihistaminic having an Atropine like effect, i.e. In asthma is dries up secretions in the bronchi ( the respiratory pipes), thus it worsens asthma. In glaucoma it can precipitate an acute angle closure glaucoma, yes it is unwise to use it. On other side effect is lethargy and in pregnancy it is also unwise to unnecessarily sedate the fetus. So, yes yes yes.
5.9k viewsReviewed >2 years ago
A 37-year-old member asked:
Please explain why is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma and pregnancy?
1 doctor answer • 5 doctors weighed in
Pharmacy 18 years experience
Side effects: Antihistamines like Diphenhydramine have side effects that effect a certain part of the nervous system (cholinergic) which would cause bronchoconstriction, and further closing of the "angle" in glaucoma (angle closure type). If you must take an antihistamine, speak to your physician about antihistamines that do not or minimally affect this system.
4.3k viewsReviewed >2 years ago
Last updated Feb 17, 2021
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