A member asked:

Do you think stem cells have the potential to cure paralysis (due to spinal cord injury) in the future?

4 doctors weighed in across 2 answers

My opinion - no: Connections within the spinal cord are very complex. Injury is often very severe with destruction of structures, infarction, necrosis, etc. Cells send fibers from the brain to the muscles through very complex pathways. A simple stem cell can not replace these connections. Atrophy of muscles will not be helped. Bowel and bladder function may not be helped.

Answered 9/28/2016

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Dr. Mark Johnson answered

Specializes in Aesthetic Medicine

Cure 4 paralysis?: In sept issue cell, a stem cell line called nsi-566 (neuralstem) was successfully used to regenerate transected spinal cords in mice, with over 57% take of grafted cells. Multiple axons were generated which covered 17 spinal segments and formed reciprocal synaptic connectivity in grey matter. Neuralstem has applied for a trial to treat chronic spinal cord injury, and thereafter likely for acute.

Answered 12/9/2013

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