Will blinking once per 2-4 seconds prevent eye strain when i'm on the computer for long hours?

Maybe: Blinking helps to distribute tears on the eye surface and may help you to feel better. Eyestrain with computer use most often arises from blur and dryness. Optimizing your glasses and use of artificial tears are good bets. Also the 20/20 rule works: look at something 20 feet away for 20 seconds every 20 minutes.

Possibly: But this is difficult to maintain. We normally blink every 10-15 seconds, so it would be hard (and straining) to force yourself to blink 5 times more often. You may be better off using artificial tears every 30-60 minutes, stare off in the distance a few times every hour and consider an eye examination to rule out the need for computer glasses.

Maybe: Our eyes are designed to see things in 3d. When you look at a computer/book etc for a long time (a 2d surface) you can strain your eyes or get dry eyes. Every 20 minutes rest your eyes for 20 seconds by looking at something at least 20 feet away.