I have taken 16 home pregnancy tests only 1 was positive, im also anemic so should i go to the hospital for a blood test?

Yes: You and your doctor should have a discussion of what is happening with you. He'll listen to you, perform an examination, and possibly order some tests to see what's going on.

Depends: If you had sex since your last period and missed your period by 4-5 days, do a home pregnancy test. If the result is negative repeat the test 4-5 days later unless you get a period by then. Use first morning urine and follow the instructions for the test carefully. If you do not wish to be pregnant, use contraception all the time, every time. You may consider implanted contraceptive, or IUD.