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A member asked:
What are the chances of having consecutive children with down's?
5 doctors weighed in across 2 answers
< 1 %: This would be extremely rare even at an advanced maternal age. If it did happen you and your partner would need to have your chromosomes checked.
Answered 5/7/2011
6.6k views
Depends on pattern: This would be rare for classical trisomy 21 but could be very high for a translation 21. I favor testing all ds infants for their chromasome pattern. If a translocation pattern is found, the parents need chromasome studies to see if one is a balanced carrier. ( ballanced 21 carriers are unaffected and have a piece of a 21 stuck on another chromasome/ but in total have all they need & no extra.
Answered 10/4/2014
6.3k views
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