A member asked:

Could taking phentermine alone cause pulmonary hypertension?

5 doctors weighed in across 4 answers

Yes: It has been associated with higher incidence of pulmonary hypertension but it is dependent on how long you are on it and certain predisposing genetic factors.

Answered 1/22/2014

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Dr. Lokesh Guglani answered

Specializes in Pediatric Pulmonology

Yes: Pulmonary hypertension occurs after consumption of appetite suppressing drugs such as Fenfluramine & Dexfenfluramine which have been commonly prescribed with phentermine. When used alone, it can still cause pulmonary hypertension & a lot of other serious side effects. Please consult your doctor to discuss the risks versus benefits before taking any medication.

Answered 9/28/2016

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Dr. Charles Burger answered

Specializes in Internal Medicine - Pulmonary Critical Care

Phentermine: While it is uncertain, a prospective surveillance study1 of 579 patients—205 with primary pulmonary hypertension and 374 with secondary pulmonary hypertension—showed no relation between primary pulmonary hypertension and Phentermine (odds ratio 0·6, 95% ci 0·2—2·2).

Answered 4/24/2015

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Dr. Charles Burger answered

Specializes in Internal Medicine - Pulmonary Critical Care

Phentermine: While it is uncertain, a prospective surveillance study1 of 579 patients—205 with primary pulmonary hypertension and 374 with secondary pulmonary hypertension—showed no relation between primary pulmonary hypertension and Phentermine (odds ratio 0·6, 95% ci 0·2—2·2).

Answered 10/23/2017

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