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A member asked:
Is methrotrexate a causative factor for pulmonary fibrosis?
3 doctors weighed in across 2 answers
Methotrexate: One very well known side effect of methotrexate(mtx) is increased inflammation in the lung. It looks like fibrosis on a ct scan. Once mtx is discontinued, symptoms and imaging typically improve within 4-6 weeks. Less frequently, mtx lung is irreversible.
Answered 9/28/2016
6.3k views
Yes: Rarely Methotrexate can cause fibrosis of the lungs. An inflammation (called pneumonitis) is more common. Lung function should be checked at least yearly while on this drug.
Answered 10/18/2016
6.3k views
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