A member asked:

What's the next step in therapy when the antidepressants and psychotherapy doesn't work at all?

9 doctors weighed in across 3 answers
Dr. Michael Sparacino answered

Specializes in Family Medicine

There are several different classes of antidepressents. If those fail, your doctor may decide to augment your therapy with another medication. Electroconvulsive therapy may be an option as well.

Answered Sep 28, 2016

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Dr. Alan Ali answered

Specializes in Psychiatry

Adjusting the antidepressant dose, switching to another antidepressant in same group, augmenting the antidepressant with another medicine, or using other techniques such as deep brain stimulation or ect, are all options. Discuss with your doctor.

Answered Apr 30, 2013

5.6k views

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Dr. Alan Koenigsberg answered

Specializes in Psychiatry

Treatment resistant depression is a common problem. In major depressions, the cause is generally biologic, and biologic treatments are the mainstay of care. The person may have low thyroid, another medical illness, bipolar disorder, a gastrointestinal disorder preventing absorption, taking antacids, and so on. Transcutaneous magnetic therapy, vagal nerve stimulation, and ECT are all safe.

Answered May 23, 2015

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