Is breast cancer risk increased with suspicious bilateral microcalcification clusters and large thickened nodule w/neg. us? how much?

Walk B4 U Run: Breast microcalcifications are very common, some of which may be associated with cancer. Radiologists will deem those suspicious enough to warrant biopsy as "birads 4 or 5". If so, the next step is to have a (nonsurgical) biopsy for definitive diagnosis. A nodule seen on mammography but not on ultrasound will also be categorized as above. Your next step is to speak w/the dr. Who ordered the mamm.

Yes: When you state that you have "suspicious" microcalcifications the radiologist means suspicious for cancer or a disease called dcis which is precancerous you should receive a birads number after a mammogram and a sono .It sounds like your birads number is a 4 which means a biopsy is advised you should definitely discuss the findings with your physician.