Apples & oranges: While both medications have indications from the fda for the treatment of fibromyalgia, they are very different. Cymbalta is an serotonin-norepinephrine reuptake inhibitor also indicated for the treatment of major depression as well as generalized anxiety disorder. Lyrica (pregabalin) works through GABA and is also indicated for seizure disorder. Your physician should be able to help you decide.
Answered 5/8/2016
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