A 49-year-old male asked:
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Can I take promethazine codeine syrup with benadryl (diphenhydramine)?

1 doctor answer
Dr. James Marx
47 years experience in Pain Management
Why?: Promethazine and Benadryl (diphenhydramine) are both antihistamines. The combination of prometh. With Codeine should be used the treatment of uncontrolled coughing. Unfortunately, the purple syrup is frequently abused in a number of unusual ways. To add Benadryl (diphenhydramine) to the combination syrup doesn't make much sense in most circumstances and could lead to at least drowsiness or worse.
Answered on Dec 12, 2019

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