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Rancho Cucamonga, CA
A 41-year-old male asked:

Can i take promethazine codeine syrup with benadryl (diphenhydramine)?

1 doctor answer2 doctors weighed in
Dr. James Marx
Pain Management 48 years experience
Why?: Promethazine and Benadryl (diphenhydramine) are both antihistamines. The combination of prometh. With Codeine should be used the treatment of uncontrolled coughing. Unfortunately, the purple syrup is frequently abused in a number of unusual ways. To add Benadryl (diphenhydramine) to the combination syrup doesn't make much sense in most circumstances and could lead to at least drowsiness or worse.

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Last updated Dec 12, 2019

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