A member asked:

Can i take promethazine codeine syrup with benadryl (diphenhydramine)?

A doctor has provided 1 answer
Dr. James Marx answered

Specializes in Pain Management

Why?: Promethazine and Benadryl (diphenhydramine) are both antihistamines. The combination of prometh. With Codeine should be used the treatment of uncontrolled coughing. Unfortunately, the purple syrup is frequently abused in a number of unusual ways. To add Benadryl (diphenhydramine) to the combination syrup doesn't make much sense in most circumstances and could lead to at least drowsiness or worse.

Answered 12/12/2019

5.6k views

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