A member asked:

Does a elevated mcv cause muscle weakness .?

4 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

MCV and anemia: Mcv or mean corpuscular volume is a measure of red blood cell volume. We use MCV to differentiate types of anemia- low volume ( microcytic), normal ( normocytic), high volume (macrocytic) anemia. Factors like vitamin deficiency, thyroid/ liver problems, drugs, bone marrow insufficiency, hemolysis can cause macrocytic anemia. Anemia can cause fatigue & muscle weakness when it is significant. D/w md.

Answered 6/10/2014

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In short: The short answer is no. The elevated MCV needs to be looked at along other parameters of CBC and could reflect B12 deficiency or folate (folic acid) deficiency and mds.

Answered 9/28/2016

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