A member asked:

Can you recommend any alternative treatments for macular hole other than surgery.?

10 doctors weighed in across 5 answers
Dr. Jay Bradley answered

Specializes in Cornea, Cataract, & Refractive (LASIK & PRK) Surgery

Macular hole: For early stage lamellar or full thickness macular holes, intervitreal injections of steroid or a vitreolysis agent can be of some benefit. For most macular holes, surgery is yourbest option.

Answered 2/24/2018

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Dr. Michael Kermani answered

Specializes in Ophthalmology

Eval by Retina MD: Some macular holes are considered partial holes or pseudo-holes. Depending on the cause and type, sometimes laser treatments, vitreal injections into the gel, or observation over time may be options. Time may also be of the essence so see a retina specialist (or second opinion) soon.

Answered 1/12/2018

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Ocriplasmin Jetrea : A new drug called ocriplasmin (trade name jetrea) is fda approved for treatment of macular hole and vitreomacular traction. It can resolve 41% of macular holes (vs. Over 95% with surgery) but without the risk of cataract progression and all the risks of vitrectomy. It it given as an in-office injection into the eye that has very minimal pain. It is expensive- $4000.

Answered 11/21/2016

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See a retina special: Some macular holes are not full-thickness and may be observed. Full thickness holes tend to need vitrectomy surgery. Ocriplasmin (jetrea) is an enzyme that can be injected into the eye in the office, but it is only somewhat effective for smaller macular holes.

Answered 3/8/2013

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Dr. Colin McCannel answered

Specializes in Retinal Surgery

Ocriplasmin: An injectable medication called Ocriplasmin can be used for repairing macular holes. The success rate is not as high as surgery, but surgery can be still be done afterward successfully. Consult with your retina specialist about this.

Answered 3/22/2016

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