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A 41-year-old member asked:

what's lactic acidosis?

1 doctor answer2 doctors weighed in
Dr. Ayo Adu
Dr. Ayo Aduanswered
Sports Medicine 14 years experience
Lactate + low pH: Lowered ph in your blood accompanied with a build-up of lactate.

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MI
A 41-year-old female asked:

Renal tubluar acidosis can it just go away and not come back?

2 doctor answers4 doctors weighed in
Dr. Pavel Conovalciuc
Family Medicine 23 years experience
Possible: There are different causes and types of rta. Vitamin d deficiency may cause it, different meds and toxins can do it, certain diseases (lupus, sjogren syndrome) may do it and finally there are some genetic causes. As you see, some of those are reversible and curable, while others (lupus, hereditary) are not, so RTA can only improve as long as the underlying cause is.
A 36-year-old member asked:

What's the pathophysiology of lactic acidosis in von gierki's disease?

1 doctor answer2 doctors weighed in
Dr. David Rosenfeld
Pain Management 27 years experience
See below: La arises from impairment of gluconeogenesis. Lactic acid is generated both in the liver and muscle and is oxidized to pyruvic acid and then converted via the gluconeogenenic pathway to g6p. Accumulation of g6p inhibits conversion of lactate to pyruvate. The Lactic Acid level rises during fasting as glucose falls. In people with gsd i, it may not fall entirely to normal even when gluc levels r nml.
San Antonio, TX
A 36-year-old male asked:

What does doc do in case of lactic acidosis ?

1 doctor answer2 doctors weighed in
Dr. Dan Fisher
Internal Medicine 27 years experience
Determine cause: Many causes of this. Treatment is directed at the underlying cause. The underlying cause is often apparent from simple review of history and observation of patient. Common causes - hypovolemia, heart failure, sepsis, alcohol, diabetes and metformin....
A 18-year-old female asked:

How do we treat lactic acidosis ?

1 doctor answer1 doctor weighed in
Dr. Jack Rubin
Nephrology and Dialysis 48 years experience
Lactic acidosis: Severe lactic acidosis (la) is often associated with poor prognosis. Recognition and correction of the underlying process is the major step in the treatment of this serious condition. Intravenous administration of sodium bicarbonate (sb) has been the mainstay in the treatment of lactic acidosis. Dialysis, peritoneal in particular, can also be used in some cases to avoid a massive sb load.
Mountain View, CA
A 51-year-old male asked:

Is there info on melas (mitochondria defect, lactic acidosis, etc.) about diagnosing a patient and looking for signs in the patient's grade-schoolers?

1 doctor answer5 doctors weighed in
Dr. Leto Quarles
Family Medicine 23 years experience
Natl Lib of Medicine: http://ghr.nlm.nih.gov/condition/mitochondrial-encephalomyopathy-lactic-acidosis-and-stroke-like-episodes is a good introductory page with links to a number of more specialized resources (both clinical and patient/family support).

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Last updated Jul 12, 2014

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