A member asked:

Is it dangerous to mix alcohol and septra (sulfamethoxazole and trimethoprim)?

4 doctors weighed in across 2 answers

Maybe: It may not be dangerous from the standpoint of a serious, adverse reaction, however, septra (sulfamethoxazole and trimethoprim) (also known as bactrim) which is an antibiotic can be made less effective if alcohol is consumed while the person is receiving it. I would check with the doctor who prescribed the septra (sulfamethoxazole and trimethoprim).

Answered 4/24/2021

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Dr. Alan Ali answered

Specializes in Psychiatry

Alcohol/Bactrim: It is a dangerous combination, not just with alcohol but also with cough medicines & mouthwashes containing alcohol. Alcohol can intensify the negative side-effects of septra, (sulfamethoxazole and trimethoprim) causing headaches, nausea, vomiting, shortness of breath & rapid heart beats, with vomiting leading to dehydration & loss of the antibiotic effect due to missed dose.

Answered 4/18/2015

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