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A member asked:
What is the pathophysiology of mycobacterium tuberculosis?
A doctor has provided 1 answer
Complex: Mtb is acquired thru respiratory route and replicates in the lung before asymptomatically disseminates to other organs. After about 6-8 weeks, the immune system starts to respond to the bug, walling the bacilli off in granulomas. Other than a positive skin test, 90% of people stay well. Of the rest, half will "reactivate" within 2 yrs and the others later sometimes due to immune suppression.
Answered 3/27/2014
5.6k views
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