A member asked:

What are the common causes of large platelets and hypersegmented neutrophils?

A doctor has provided 1 answer

Vitamin & leukemias.: Hypersegmented neutrophils are seen with vitamin b-12 and folate (folic acid) deficiency, while large platelets can be in myelophthisic disease, like myelofibrosis and leukemias. These are conditions that displace the precursor cells from the bone marrow into the peripheral blood.

Answered 9/1/2013

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