Are there drug interactions between cocaine and melatonin supplements?

Probably not: Melatonin is a hormone that is naturally found in your brain which we believe helps us regulate our sleep cycle. It is not known what happens if a person takes it in a supplement form for long periods of time (even just weeks or months) so most doctors like myself do not recommend it. Using cocaine, with melatonin or not, is a really bad idea. Plus, last i heard, it's illegal.