A member asked:

Okay but what if i'm the only one in my family and family's background to have it mines a mild case of neurofibermitosis would my child's be worse?

4 doctors weighed in across 2 answers

New NF case: Many cases of nf represent a spontaneous new mutation. If you have a mild case, it is now in your dna and can be passed on to your children as the same form. As an autosomal dominant, your risk of passing it is 50% with any conception. The form you may pass should remain the same intensity as you have. Contact a genetic counselor for a broader eval & information.

Answered 8/29/2012

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Dr. Gerald Mandell answered

Specializes in Nuclear Medicine

Cannot predict: Scientists don't know exactly why symptoms vary so much, even among people from the same family. Genetics has a lot to do with it and likely that each patient's unique genetic makeup influences the severity of his or her symptoms. Even in family with known nf1 can not predict severity of symptoms in family members. In about half of all cases, a person inherits the mutated gene from a parent.

Answered 9/7/2013

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