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A 24-year-old member asked:

What does malignant mean?

2 doctor answers6 doctors weighed in
Dr. Michael Thompson
Hematology and Oncology 20 years experience
Cancer: Malignant = cancer i can't think of an exception, but one may exist.
Dr. Edwin Schuller
Family Medicine 45 years experience
Think of malignant as uncontrolled and unstoppable growth of tissue either locally or distantly from the original site.
Jul 26, 2012
Dr. Michael Thompson
Hematology and Oncology 20 years experience
Provided original answer
Good comment.
Jul 26, 2012
Dr. Myron Arlen
Surgical Oncology 64 years experience
Transformation: When a normal cell transforms to malignancy a proto oncogene transforms to a complete oncogene producing a protein or proteins to allow the cell to become aggressive and invasive as well as immortal. A transcriptional protein like FGARAT appears allowing aggressiveness, followed by overexpression of telomerase for longevity, and then matrix metallo proteinase allowing blood vessel invasion.

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Last updated Aug 11, 2015

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