Hi is susten(progesteron) safe to use in second and third trimester in pregnancy?

Tell OBs more please: Please tell us a bit more about the pregnancy, risk factors, reason for progesterone. You may add that information as a separate question or as part of comments. In the meantime i will refer this to some OB specialists for additional input. Thanks for asking this interesting question.

Sure.: Crinone, (progesterone gel) prochieve and Makena are all fda approved for use in pregnancy. Progesterone is a natural hormone that exists in the maternal body in high concentrations all through pregnancy - but additional supplementation has been proven to prevent preterm birth in at-risk women. Talk to your obstetrician about this to see if it is a good choice for your pregnancy. It is a safe and effective drug.